Neural Mechanisms Mediating Inhibitory Influences of Hyperthermia, Fever and Age on Water Intake

Grant number: 232306

Abstract

An adequate intake of fluid following losses of body water that can occur as the result of sweating in hot weather, exercise, vomiting or diarrhoea is necessary so that dangerous levels of dehydration do not occur. Thus, it is important for our health that thirst is properly stimulated when we do become dehydrated, in order that we are aware that we must drink water. There may be conditions in which the thirst mechanism is inhibited, and the aim of these experiments is to identify and understand mechanisms by which the thirst mechanism in the brain is supressed. We have observed that a high body temperature may have an inhibitory influence on thirst in rats, and it is also known that thirst ..

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Related publications (10)

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Thirst motivates animals to seek fluid and drink it. It is regulated by the central nervous system and arises from neural and chem..

University of Melbourne Researchers

Michael McKinley